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Food Pharmacy
Spring 1999
The fats of life
cholesterol up close and personalMedium-chain triglycerides (MCT) may not have a neutral effect on cholesterol as previously believed, say researchers at the University of Texas Southwestern Medical Center in Dallas.

In 9 middle-aged men, a trial of MCT oil boosted cholesterol levels an average of 29 milligrams per deciliter of blood. 

Until further studies confirm these findings,  investigators recommend that patients and athletes taking MCT oil should have cholesterol levels monitored. 


Reference:
Cater NB et al. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans Am J Clin Nutr 1997 65(1):41-5
Related links:
MCT oil from health-food stores not as healthy as touted  Short article about the MCT cholesterol study at UT Southwestern headed by Dr. Nilo Cater. 

MCT oil
Another brief report on the MCT cholesterol study.

FAQs on MCT
Michael Darnley, R.D., explains the composition of MCT oil and its therapeutic applications.

Mead-Johnson Pharmaceuticals
Basic information on their MCT product.



To read about treatment and dosage for MCT oil in CPT II deficiency, see Chain reaction and Treatments survey results


To read MCT advice from Bruce Cohen, M.D., see Double take.
  

The medium-chain fatty acids are quickly absorbed and transported to the liver. The long-chain fats have to be processed in a different way. The popular belief was that medium-chain fats wouldn’t hurt us and would give us access to quick energy. What our research suggests is that the liver reuses medium- chain fats as building blocks and resynthesizes them into longer chain fatty acids. 
         --Nilo Cater, M.D.


MCT oil is unpalatable for some people and may cause diarrhea or GI
distress.
    --Michael Darnley, R.D.
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